Structure and Mechanisms of Action. Allopurinol (4-hydroxypyrazolo[3,4-d]pyrimidine) is a structural analog of hypoxanthine, while its active metabolite oxypurinol is a structural analog of xanthine (Fig. 13-1). The mechanisms of action of allopurinol and oxypurinol are summarized in Table 13-1. Both allopurinol and oxypurinol inhibit XO
This is primarily where allopurinol and febuxostat are different. Allopurinol and its metabolites are structural analogues of both purines and pyrimidines
Allopurinol is a drug that is used to decrease uric acid that causes gout. This lesson will discuss the mechanism of action and structure of allopurinol.
The sodium form of allopurinol, which is a structural isomer of hypoxanthine. Allopurinol inhibits xanthine oxidase, an enzyme that converts oxypurines to
Chemical structure of allopurinol Chemical structure of allopurinol DSC profile of allopurinol. 30 % water–ethanol, 20 % ethyl. Solubility mole fraction
Allopurinol Description: Mechanism of Action: Allopurinol is a structural analogue of hypoxanthine that acts on purine catabolism without disrupting the
IV: 1.21 ± 0.33 hours (allopurinol); 23.5 ± 4.5 hours (oxipurinol). Chemical Structure. Chemical Structure Image Allopurinol Source: National Center for
Allopurinol is a structural isomer of hypoxanthine. Certain findings suggested that oxypurinol, the major metabolite of allopurinol, could attenuate 5-
structure image Molecular structure of Allopurinol, CAS Number: . Molecular structure of Allopurinol, CAS Number: . Receive special offers
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